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The Signal Your Skin Has Been Waiting for

Rejuvenate Extract: Powered by Energy Signal AMP.

Tested for Sensitive Skin
Fragrance-Free
Clinically Tested
Made in Japan
Hypo-allergenic

MEET REJUVENATE EXTRACT

Powered by Japanese Longevity Science. One Serum. Twice a day. 

Fragrance-free, fast-absorbing formula

Clinically proven to improve visible signs of aging

Supports skin's healthy skin renewal cycle

Energy Signal AMP: The Molecule that Energizes Everything.

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OTSU SKINCARE RESEARCH INSTITUTE

Born in Japan in 1990, Otsu Skincare Research Institute exists to push the boundaries of skin science.

Two decades of research produced Energy Signal AMP®—a clinically proven, world-first ingredient that amplifies natural skin regeneration and redefines brightening, recognized by Japan's Ministry of Health, Labour and Welfare.

Rejuvenate Extract

CLINICAL RESULTS

3X¹

Increase in hydration.

29%²

Visible wrinkle reduction.

9%³

Reduction of visible age spots.

1. 24 weeks, N=10, 2000 | 2. 24 weeks, N=10, 2000 | 3. 8 weeks, N=8, 2008

Questions, Answered.

Everything you need to know before you get started.

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